Low prevalence of infection by HTLV-I in populations at risk for HIV in Djibouti
Identifieur interne : 001585 ( Main/Exploration ); précédent : 001584; suivant : 001586Low prevalence of infection by HTLV-I in populations at risk for HIV in Djibouti
Auteurs : E. Fox [Égypte, États-Unis] ; N. T. Constantine [Égypte, États-Unis] ; E. A. Abbatte [États-Unis] ; E. A. Said-Salah ; G. RodierSource :
- Annales de l'Institut Pasteur / Virologie [ 0769-2617 ] ; 1988.
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Abstract
Summary: In order to determine whether HTLV-I (a recently discovered retrovirus causing T-cell leukaemias and lymphomas, as well as tropical spastic paraparesis) was present in Djibouti in 1988, we investigated 576 subjects belonging to various groups at risk of acquiring HIV, a related retrovirus transmitted analogously to HTLV-I. Sera were screened by a commercial agglutination assay and confirmation of repeatedly reactive sera was performed by specific Western blot analysis. Four sera were strongly positive for HTLV-I by Western blotting, while one serum displayed equivocal reactivity. All positive sera came from young women who engaged in prostitution. This accounted for an HTLV-I seropositivity rate of 0.7% (95% CI, 0.03–1.4%) in the total study population and 1.2% (95% CI, 0.02–2.4%) in the population engaged in prostitution. We concluded that in Djibouti in June 1988, HTLV-I was present but that the prevalence of infection in high risk indivduals was very low.
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DOI: 10.1016/S0769-2617(88)80080-7
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Sera were screened by a commercial agglutination assay and confirmation of repeatedly reactive sera was performed by specific Western blot analysis. Four sera were strongly positive for HTLV-I by Western blotting, while one serum displayed equivocal reactivity. All positive sera came from young women who engaged in prostitution. This accounted for an HTLV-I seropositivity rate of 0.7% (95% CI, 0.03–1.4%) in the total study population and 1.2% (95% CI, 0.02–2.4%) in the population engaged in prostitution. We concluded that in Djibouti in June 1988, HTLV-I was present but that the prevalence of infection in high risk indivduals was very low.</div></front></TEI><affiliations><list><country><li>Égypte</li><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><noCountry><name sortKey="Rodier, G" sort="Rodier, G" uniqKey="Rodier G" first="G." last="Rodier">G. Rodier</name><name sortKey="Said Salah, E A" sort="Said Salah, E A" uniqKey="Said Salah E" first="E. 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